clinical efficacy to Moderna therapies, and extrapolating from these observations to enable future Moderna therapies. It is our intention to expand the discovery process from pre-clinical studies into the realm of clinical investigation. Reporting to the Executive Director of Clinical and Translational Computational Oncology, the Principal Scientist will be a key member of a high performing team responsible for understanding the clinical mechanisms of Moderna cancer therapies, from cancer vaccines to other types of immune engagers for the treatment of cancer.
You will be an innovative and collaborative computational scientist with knowledge of clinical trials, translational analytics,
skill in the area of mining genomics and understanding of oncogenic and immune-oncological mechanisms with high learning agility. In collaboration with Translational Medicine scientists, you will develop and apply computational methods to analyze large datasets coming from the clinical studies in Moderna's oncology portfolio and publicly and commercially sources datasets.
The candidate must thrive in a fast-paced environment with high expectations. Integrity, ability to share experimental issues and troubleshoot, curiosity, collaborative spirit, respect for people, exemplary work ethic and setting the bar high are key values to thrive in our Team. Here's What You Will Do: Use computational
approaches to analyze complex multimodal internal clinical and publicly available or commercial patient datasets in order to extract clinically actionable insights Analyze complex multi-omics data across various data modalities and connect insights and observations to clinical endpoints Focus on mechanistic questions related to a program in relationship to the broader Moderna oncology portfolio and the landscape of existent oncology therapies.
Work with internal groups at Moderna as well as external partners to solve problems using cutting-edge data visualization and analysis Independently communicate findings to multiple parties and contribute to research publications Collaborate closely with Translational Medicine and Oncology scientists to ensure that data is effectively utilized for high level impact Here's What You'll Bring to the Table: Minimum Qualifications Ph D plus 5 or more years of experience in a quantitative field (i.
e. bioinformatics, computational/systems biology) within industry drug discovery and development setting Strong programming ability in a language such as Python or R Experience analyzing genomics data from clinical trials in an industry setting Experience with the analysis of NGS data Experience with applying machine learning methods (ML/AI) to biological data Preferred Skills Strong grounding in the state-of-the art with respect to single cell biology and computational analysis Ability to quickly conceive and implement custom computational methods and algorithms and apply them to large data sets Experience using computational methods to extract insight from large datasets Experience working on problems involving complex biological systems at high-resolution Creative problem solver who seeks finding useful biologically relevant information in data Experience working in an applied biological field such as immunology, cancer, or immune-oncology Experience with m RNA therapies and LNP delivery technologies Experience with applying machine learning methods (ML/AI) to analyzing clinical images (i.
e. H&E stains) Strong scientific background, including an understanding of molecular biology and NGS techniques Experience working with multiple sequence alignments and large sequence datasets Familiarity with common bioinformatics tools for NGS data analysis Ability to work both independently and collaboratively Proficiency with high performance computing, preferably on public clouds (i. e. AWS, GCP, Azure) Outstanding written and verbal communication skills, ability to work with colleagues from diverse scientific backgrounds and cultures Moderna is pleased to provide you and your family with a comprehensive and innovative suite of benefits, including: Highly competitive and inclusive medical, dental and vision coverage options Flexible Spending Accounts for medical expenses and dependent care expenses Lifestyle Spending Account funds to help you engage in personal enrichment and self-care activities Family care benefits, including subsidized back-up care options and on-demand tutoring Free premium access to fitness, nutrition, and mindfulness classes Exclusive preferred pricing on Peloton fitness equipment Adoption and family-planning benefits Dedicated care coordination support for our LGBTQ+ community Generous paid time off, including: • Vacation, sick time and holidays• Volunteer time to participate within your community• Discretionary year-end shutdown• Paid sabbatical after 5 years; every 3 years thereafter Generous Paid Leave offerings, including 18 weeks of 100% paid parental leave for all new parents 401k match and Financial Planning tools Moderna-paid Life, LTD and STD insurance coverages, as well as voluntary benefit options Complimentary concierge service including home services research, travel booking, and entertainment requests Free parking or subsidized commuter passes Location-specific perks and extras!
About Moderna Since our founding in 2010, we have aspired to build the leading m RNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world. By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture.
Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities. We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U. S. If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit /careers to learn more about our current opportunities. Moderna is a smoke-free, alcohol-free and drug-free work environment.
Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply! Moderna is proud to be an equal opportunity workplace and is an affirmative action employer. Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, interaction, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, interactionual orientation, marital or familial status, or any other personal characteristic protected under applicable law.
Moderna is an E-Verify Employer in the United States. We also consider qualified applicants regardless of criminal histories, consistent with legal requirements. Belonging, Inclusion, and Diversity are critical to the success of our company and our impact on society. We're focused on attracting, retaining, developing, and advancing our employees and believe that by cultivating diverse experiences, backgrounds, and ideas, we can provide an environment where every employee is able to contribute their best.
Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the Talent Acquisition Partner or contact the Accommodations team at xyz X@. (EEO/AAP Employer) #LI-JL2
Research & Development (R&D) jobs involve creating new products or improving existing ones through innovative processes in a variety of industries such as technology, pharmaceuticals, engineering, and consumer goods. R&D professionals are typically highly educated and skilled in scientific research, product development, and problem-solving. They work to push the boundaries of knowledge, often in laboratory settings or in the field, and contribute directly to a company's growth and competitiveness by turning novel ideas into marketable solutions. Such roles demand creativity, technical expertise, and a forward-thinking mindset geared towards technological advancement and market trends.
Research & Development (R&D) jobs are positions focused on creating new products, enhancing existing ones, or discovering new knowledge to advance technology. Individuals in these roles typically work for companies aiming to innovate and maintain competitiveness. Key characteristics of R&D jobs include problem-solving, creativity, a strong technical background, and the ability to work collaboratively. R&D professionals often engage in experimental testing, data analysis, and continuous learning to achieve breakthroughs in sciences, engineering, or other fields. The nature of these jobs is inherently dynamic, requiring adaptability and a forward-thinking mindset.
Research & Development (R&D) jobs involve creating new products or improving existing ones through innovative processes. Professionals in these roles conduct experiments, analyze data, and turn concepts into practical solutions. R&D is pivotal in industries such as pharmaceuticals, technology, and engineering, and is characterized by a focus on innovation, problem-solving, and continuous learning. R&D positions often require advanced education and a strong foundation in scientific or technical disciplines. These roles are essential for driving progress and maintaining competitive edges in marketplaces.
with computational biologists, immunologists, and translational biologists in Oncology Research support cancer vaccine discovery, translational research, and clinical development. Here's What You'll Do Identify immunogenomics datasets and tools (such as IEDB, IMGT) and build analytical solutions for oncology target identification and design Using public and proprietary sequencing datasets, design and interpret bioinformatics analysis to derive insights for biological hypothesis and biomarker discovery Stay up to date with current state-of-the-art practices of multi-omics data analysis and interpretation, particularly in the fields of cancer immunogenomics Collaborate closely with computational
and experimental biologists to support oncology research and clinical development Here's What You'll Need (Minimum Qualifications) Ph.
D. in Bioinformatics, Computational Biology, Systems immunology, or related quantitative discipline Minimum 2 years Bioinformatics, Computational Biology, or related experience in industry Experience with -omics data analysis, including RNA-seq, WES, immune repertoire sequencing Strong coding skills with R and/or Python Experience with high performance computing and AWS cloud computing platform Here's What You'll Bring to the Table (Preferred Qualifications) Prior experience leading the development and productization of prediction algorithms, ideally in
the bioinformatics space Strong problem-solving skills and a results-oriented mindset Demonstrated cross-functional collaboration with multidisciplinary teams Curious about exploring a new pathway for drug discovery Be bold in proposing and delivering on creative experimental designs and ideas Moderna is pleased to provide you and your family with a comprehensive and innovative suite of benefits, including: Highly competitive and inclusive medical, dental and vision coverage options Flexible Spending Accounts for medical expenses and dependent care expenses Lifestyle Spending Account funds to help you engage in personal enrichment and self-care activities Family care benefits, including subsidized back-up care options and on-demand tutoring Free premium access to fitness, nutrition, and mindfulness classes Exclusive preferred pricing on Peloton fitness equipment Adoption and family-planning benefits Dedicated care coordination support for our LGBTQ+ community Generous paid time off, including: • Vacation, sick time and holidays• Volunteer time to participate within your community• Discretionary year-end shutdown• Paid sabbatical after 5 years; every 3 years thereafter Generous Paid Leave offerings, including 18 weeks of 100% paid parental leave for all new parents 401k match and Financial Planning tools Moderna-paid Life, LTD and STD insurance coverages, as well as voluntary benefit options Complimentary concierge service including home services research, travel booking, and entertainment requests Free parking or subsidized commuter passes Location-specific perks and extras!
About Moderna Since our founding in 2010, we have aspired to build the leading m RNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world.
By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities. We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U. S. If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit /careers to learn more about our current opportunities.
Moderna is a smoke-free, alcohol-free and drug-free work environment. Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply! Moderna is proud to be an equal opportunity workplace and is an affirmative action employer. Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, interaction, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, interactionual orientation, marital or familial status, or any other personal characteristic protected under applicable law.
Moderna is an E-Verify Employer in the United States. We also consider qualified applicants regardless of criminal histories, consistent with legal requirements. Belonging, Inclusion, and Diversity are critical to the success of our company and our impact on society. We're focused on attracting, retaining, developing, and advancing our employees and believe that by cultivating diverse experiences, backgrounds, and ideas, we can provide an environment where every employee is able to contribute their best.
Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the Talent Acquisition Partner or contact the Accommodations team at xyz X@. (EEO/AAP Employer) #LI-JL2
the benefit of patients. We have an exciting opportunity to join Sanofi at our Cambridge Crossing research campus as a (senior) distinguished scientific leader working in translational immunology in our type 2 immunology cluster. Focusing on Dupixent, an approved biological medication for several diseases including Atopic Dermatitis and Asthma, your position will direct our research strategy for enhancing our understanding and competitiveness of this exciting therapy.
This translational immunology role will incorporate learnings from research and clinical studies into strategies developed together with our partners in Development, Medical Affairs and Commercial to drive our research directions
and maximize the value of Dupixent. This position will also assume responsibility for scientific leadership of Itepekimab, currently in clinical development for COPD.
Working in a highly matrix environment, this position will involve all aspects of the medical business and require skills aligned with being able to integrate and contribute to decisions in Research, Development, Medical Affairs and Commercial. The incumbent must be a strong communicator and skilled in managing stakeholder relationships. There will also be significant opportunities to develop and contribute to external collaborations with renowned academic institutions and work closely with our partners at Regeneron. We
are searching for someone with a strong knowledge of immunology, particularly Type 2 diseases, and an ability to lead through strategic coordination and collaboration.
The position will lead a team of dedicated scientists and therefore significant managerial and mentorship experience is essential. The incumbent will work independently, pro-actively and serve as an impactful contributor to transverse initiatives to support our business objectives, including maintaining a national and international reputation in the external scientific community through high impact publications, productive scientific collaborations, and active participation in conferences.
This position reports directly to the Type 2 Immunology Cluster Head. Job Responsibilities: Identifies and develops scientific strategies to support research business goals and lead a translational immunology research team to initiate, design, and execute research experiments. Build strong collaborative relationships with our internal and external partners to ensure programmatic activities relevant to our clinical experience and research interests. Work collaboratively with multifunctional teams across Sanofi to leverage resources and ensure our preclinical research efforts are aligned with strategies to support the successful development of Dupixent and Itepekimab.
Identify multidisciplinary solutions and make complex decisions and recommend a course of action to troubleshoot issues. Develop and manage relationships with external academic collaborators Communicate research through peer-reviewed publications and presentations to internal and external audiences Maintain a thorough and up to date knowledge of scientific and medical developments in the field and incorporate into in-house strategies as appropriate. Understand and adhere to corporate standards regarding code of conduct, safety, appropriate handling of materials such as controlled drug and radioactive compounds.
Supervise a team several Ph. D. and non-Ph. D. scientists, guide and evaluate the performance of those individuals, and be accountable for the effective performance of the team/individuals. Basic Qualifications: Ph D in Immunology or a related field with 12+ years of related work experience, including successful postdoctoral training and experience. Possesses leading-edge scientific understanding and working knowledge of principles, concepts, and practices in the field of type 2 immunology, including peer-reviewed publications and presentation history in notable scientific journals and forums.
Outstanding track record of scientific publications, presentations, patents, projects as senior author/contributor. Demonstrates continuous growth in depth and breadth of personal scientific knowledge and understanding of strategic goals of group, team, and company Strong managerial and mentorship skills and experience Possesses strong communication and presentation skills and an exceptional work ethic. Acts independently to achieve pre-determined goals and objectives Able to identify multidisciplinary solutions to problems, make complex decisions and recommend a course of action to senior level management Highly motivated, independent, collaborative, and able to communicate effectively with a cross-functional team Exercises foresight and judgement in planning, organizing, and guiding complex projects Fosters a culture of employee growth and development Preferred Qualifications: Direct research and strategic experience in Type 2 immunological diseases Experience with translational medicine, including precision immunology Proven track record in the medical industry.
At Sanofi R&D North America, we deliver meaningful solutions for patients.
We transform science into breakthrough, best-in-class and first-in-class medicines and vaccines. We believe in creating a diverse and inclusive workforce - and workplace - which brings together the collective brainpower of over 2,000 colleagues and provides you with an exciting place to grow and develop. We set the bar high, and we deliver. Join us and together we will build on our trusted legacy of breakthroughs for society. Sanofi Inc. and its U. S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce.
All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; interaction, gender, gender identity or expression; affectional or interactionual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law. #GD-SA #LI-SAAt Sanofi diversity and inclusion is foundational to how we operate and embedded in our Core Values.
We recognize to truly tap into the richness diversity brings we must lead with inclusion and have a workplace where those differences can thrive and be leveraged to empower the lives of our colleagues, patients and customers. We respect and celebrate the diversity of our people, their backgrounds and experiences and provide equal opportunity for all.
Administrative or clerical jobs involve a range of office-related tasks that support the day-to-day operations of a business. Employees in administrative roles are often responsible for managing records, answering phones, scheduling appointments, preparing documents, and performing data entry. These positions typically require strong organizational skills, attention to detail, proficiency with office software, and the ability to communicate effectively. Clerical workers are key in ensuring that an office runs smoothly and efficiently, acting as the backbone to the administrative structure of an organization.
Healthcare jobs encompass a variety of roles within the medical industry, dedicated to providing care and improving the health and well-being of patients. These positions include doctors, nurses, therapists, technicians, and support staff among many others. Key features of healthcare jobs often involve direct patient care, specialized knowledge in fields such as cardiology or oncology, and a strong commitment to ethical practices and continuous learning to keep abreast of medical advancements. Notably, healthcare careers are known for their resilience in job markets, offering stability and a sense of purpose as professionals work to heal and help others.
Healthcare jobs encompass a wide range of positions within the medical industry dedicated to providing care and improving patient health. Roles include doctors, nurses, therapists, technicians, and administrative staff working in settings like hospitals, clinics, and private practices. These jobs are characterized by a strong emphasis on patient care, continuous learning due to advances in medical knowledge and technology, and often require certifications or specialized education. The field is known for its resilience, job security, and a deep sense of fulfillment as professionals contribute to the well-being of individuals and communities.
Healthcare jobs encompass a range of professions within the medical industry dedicated to maintaining and restoring human health. These positions can include doctors, nurses, therapists, technicians, and administrative support, among others. Key characteristics of healthcare jobs are a strong emphasis on patient care, continuing education due to constant advances in medical science, and the need for a collaborative approach among different healthcare professionals. Additionally, healthcare jobs often require certification or licensing and are known for their resilience in the job market due to the essential nature of health services.
HR & Recruiting Jobs focus on attracting, hiring, and maintaining a workforce within an organization. These roles involve a multitude of tasks such as posting job openings, screening candidates, conducting interviews, managing employee relations, and ensuring compliance with labor laws. Key characteristics include strong communication skills, the ability to handle confidential information, and a knack for understanding both organizational needs and employee well-being. HR professionals not only optimize recruitment processes but also play a vital role in shaping company culture and fostering a productive work environment.
Facilities/Maintenance Jobs refer to positions responsible for the upkeep and repair of buildings, grounds, and equipment. Individuals in these roles handle tasks such as routine maintenance, troubleshooting, and fixing issues to ensure that the physical environment of a workplace remains safe and functional. This sector requires a mix of technical knowledge, problem-solving abilities, and often physical labor. Workers might be on call for emergencies, implying a need for flexibility and a proactive attitude. Overall, these jobs are essential for preserving the operational efficiency and longevity of an organization's physical assets.
Hospitality and travel jobs refer to career opportunities within the service industry focused on customer satisfaction and experiential services. These roles can vary widely and include positions in hotels, restaurants, cruise ships, theme parks, and other travel-related enterprises. Key features of hospitality jobs often involve interpersonal interactions, cultural sensitivity, and a commitment to providing high-quality service. Employees are typically expected to enhance the guest experience, handle logistics, and ensure safety and comfort, all while maintaining a friendly and welcoming disposition. Travel jobs, more specifically, may also include roles that entail planning and organizing travel itineraries for individuals or groups, often requiring strong organizational skills and an in-depth knowledge of travel destinations and regulations.
Banking jobs refer to employment opportunities within the financial industry, specifically within banks, where individuals handle monetary transactions, manage financial assets, provide advice on financial services, and support the economic infrastructure. These roles often require strong numerical skills, keen attention to detail, and an understanding of financial regulations. Sector jobs can range from teller positions to investment banking analysts, each with a focus on financial integrity, customer service, and contributing to the bank's profitability. As the banking sector evolves with technology, many roles also involve adapting to digital banking platforms and innovative financial products.
Restaurant or food service jobs encompass a variety of roles within the dining industry, including positions like servers, chefs, kitchen assistants, dishwashers, hosts, and restaurant managers. These jobs are characterized by their fast-paced environment, customer service focus, and the need for strong teamwork. Employees in this field often work irregular hours, including evenings, weekends, and holidays, to accommodate the dining hours of patrons. They require excellent communication skills, the ability to work quickly and efficiently, and a passion for food and hospitality. Despite the demanding nature, these jobs offer valuable experience in customer relations and operations management.